Scientist / analytical development Job at Tessera Therapeutics, Somerville, MA

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  • Tessera Therapeutics
  • Somerville, MA

Job Description

Your Experience Includes…

  • BS in analytical chemistry, biochemistry, or relevant discipline with 8+ years of relevant experience, or M.S. with 6+ years relevant industry experience, or PhD with 1+ years industry experience.
  • The application of a diverse set of analytical assays, with strong background in LCMS (required) and HPLC.
  • Experience with RNA or Oligonucleotide analytical chemistry and biophysical techniques is helpful, preferably in biopharmaceutically relevant systems.
  • Analyzing and interpreting written material, in various forms including tables and spreadsheets, as well as quantitative and qualitative data.
  • Writing clear and concise reports and memos.
  • A high level of personal and spatial organization.
  • Strong interpersonal and communication skills.
  • A learning and betterment mindset.


You are interested in…

  • Advancing existing and establishing new methods using mass spectrometry, HPLC and electrophoretic methods to characterize RNA molecules (oligos and/or mRNA).
  • Representing the Analytical Development team in cross-functional meetings, presenting results and providing scientific input as needed.
  • Participating in in-depth investigations, including orthogonal method evaluation, understanding RNA and oligonucleotide stability, and characterizing impurities in a CMC setting.
  • Exploring new technology and software to strengthen and streamline RNA and oligonucleotide characterization workflows.
  • Maintaining external awareness of advances in the field through keeping updated on relevant publications, attending conferences and workshops.
  • Effectively collaborating within the Analytical team and with other functional teams.
  • Using scientific and technical expertise for instrument maintenance and troubleshooting.
  • Training and mentoring junior scientists as needed.
  • Performing assays, analyzing, interpreting, and reporting results in appropriate format (ELN, analytical reports, and presentations).
  • Performing additional duties and responsibilities as required.


About You:

You have an interest in developing and implementing RNA molecule characterization assays. You are able to work well independently or as part of a team, have impeccable attention to detail, and enjoy working in a fast-paced environment.

Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence. 

Meet Your Manager:

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.

Felipe Gazos Lopes – Associate Director, Analytical Development

Originally from Brazil, Felipe obtained his PhD from The University of Texas at El Paso. He was a Postdoctoral Fellow with the Harvard T.H. Chan School of Public Health, later joining Sanofi Genzyme and Dicerna. Felipe was then hired to Tessera in 2020, where he specializes in chromatography and mass spectrometry for platform development. Outside of work, he lives in MA with his therapist wife and Chihuahua-mix dog. Felipe enjoys meditating, reading, hiking, cooking and rowing.

Meet Your Talent Partner:

Annie Edminster (she/her) – Employee Experience and Talent Lead

Originally from Maine, Annie obtained her Bachelor of Science from Syracuse University. She spent eight years in Biotech, Engineering and Tech agency recruitment, then joined Tessera in 2022. Annie loves watching her new hires grow in their careers and getting to know her colleagues from all over the world! Outside of work, she lives in NH with her robot-building husband, two feisty daughters, and two Siberian cats. Her Love Languages include creating playlists, sending memes, and sharing books.

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com

Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.

Job Tags

Full time, Local area,

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